In a patient experiencing anaphylaxis, how should pharmacists administer epinephrine?

In cases of anaphylaxis, administering epinephrine is crucial as it is the first-line treatment for this severe allergic reaction. Epinephrine works by rapidly reversing the symptoms of anaphylaxis, such as airway constriction, hypotension, and skin reactions. It helps to increase blood flow, open airways, and reduce swelling, making it vital for stabilizing the patient until further medical assistance can be provided.

The other options, while containing elements that might be relevant in certain contexts (such as the consideration of additional medications or administration routes), do not prioritize the immediate and critical role that epinephrine plays in managing anaphylaxis. For instance, while diphenhydramine can be used to help with allergy symptoms, it is not sufficient on its own and should not delay the administration of epinephrine, which should be given as quickly as possible.

Administering epinephrine intramuscularly in the deltoid is important, but it is essential to recognize that this is part of the action taken after determining that epinephrine is indeed the first-line treatment. The recommendation to administer it every 2 minutes until EMS arrives may not reflect the standard practice, as it is more appropriate to follow established dosing guidelines and